Many people want to improve their nutrition and overall health naturally. If you’re considering trying CBD for weight loss (or just to improve your general nutrition), Christy Thiel, our National Director of Education and Partner Relations at Seed2System weighed in on some of the most frequently-asked questions about this topic. Here’s what you need to know.


cbd for weight lossCannabidiol (or CBD) is an oil derived from the hemp plant. It’s an adaptogen, that is a non-toxic plant that can help stabilize the body, reduce stress, and return it to homeostasis. In general, CBD works on three major mechanisms that impact your overall health and weight loss. These include the:

  • Endocannabinoid system
  • Inflammation response
  • Parasympathetic nervous system

Your endocannabinoid system is responsible for regulating your metabolism and body temperature, both of which play a part in weight loss.

In addition, CBD acts on the inflammatory response in your body. This is a normal and protective response our body has that can unfortunately kick into high gear under certain circumstances, like chronic stress or other health conditions. In turn, this can lead to weight gain and a myriad of other symptoms.

Finally, our parasympathetic nervous system is the system that triggers the “rest and digest” response. This is the opposite of the “fight or flight” mechanism that’s dominant under chronic stress. CBD oil has the potential to calm this chronic stress response.


So, how does CBD work on these three mechanisms in the body to promote weight loss? As Thiel explains, research showcases a few major benefits of CBD for your body.


By helping the body stimulate CB1 and CB2 cannabinoid receptors in the brain, CBD oil may actually work to both speed up your metabolism while reducing your appetite.

A 2017 study found that feeding behaviors in mice changed significantly when CB cannabinoid receptors were stimulated. These changed behaviors resulted in weight loss and a more regulated metabolism.

These results were first achieved in a 2015 study of mice that focused on the CB2 receptor (CBD’s primary target). This study also found a reduction in food intake, fatty tissue, and inflammation.


It’s a vicious circle: inflammation increases your chances of obesity, and obesity increases inflammation. Chronic inflammation also increases both the size of fat molecules and their density—both of which (you guessed it) can lead to obesity.

In some cases, oxidative stress is the culprit behind this increased inflammation. Oxidative stress occurs when free radicals overtake the body’s ability to counteract them with antioxidants. However, CBD oil can actually help reduce inflammation by reducing oxidative stress in the body.

Other research found that CBD oil also had the following effects on inflammation:


Stress affects every system in the body, and chronic stress can lead to weight gain. With additional stress, the body also begins to store fat around the organs, the most dangerous place for it. Not only is more fat created and stored due to stress, but the type of fat (white, as opposed to healthier “brown” fat) is also more dangerous.

Adaptogenic CBD can promote the production of “brown” fat, a process that protects against some of the most dangerous health conditions linked to obesity. This “browning” also helps to regulate body weight and maintain a stable body temperature, both of which are associated with weight loss. CBD oil may also help the body to use fats more efficiently.

Overall, adaptogenic CBD helps the body combat and counteract the damaging effects of stress, including obesity.


Another factor in your stress response is disrupted sleep. Thankfully, poor sleep is another type of vicious cycle that CBD has the potential to disrupt.

When poor sleep becomes chronic, cortisol production in the body increases. People who use caffeine to stay awake further increase their cortisol production. Additionally, sleep-deprived people consume more calories in unhealthier forms than those who are well-rested.

CBD oil can improve poor sleep, especially poor sleep linked to anxiety (which is itself tied to stress). With each solid night of sleep, cortisol production evens out, and the stress response calms.


There is good evidence that CBD for weight loss has the potential for positive results, but which types of CBD are best for weight loss?

Christy Thiel notes that the best types of CBD utilizes the plant in its most complete and natural state, stating:

“The best products for weight loss are full-spectrum and broad-spectrum hemp products. These products have more than CBD in them. Since the endocannabinoid system regulates metabolism, we want to support it with nutrient density that comes from hemp in nature’s ratios. Full-spectrum CBD includes as many cannabinoids and terpenes that were in the plant naturally.”

Many consumers utilizing CBD for weight loss are also curious about the proper dosage. The answer? It depends. A good rule of thumb is not too much, but just enough. Because everyone’s body chemistry, lifestyle, and weight loss goals are different, the dose for each person will be as unique as they are.

cbd for weight lossThe best approach is to observe your progress over time and make adjustments as needed. Seed2System’s 1500 mg gold tincture (and our 600 mg silver tincture) are a great place to start. Talk to your doctor and the producer before you start and titrate your dosage as needed.

And just one caution: CBD oil is legal with less than .3% of THC in the final product, like we produce at Seed2System. However, this small amount may be enough to appear on a drug screen, so speak to your employer before using if that’s a concern for you.


The origins of CBD oil for weight loss matters. Many consumers may think that all brands and products are created equal, but that’s unfortunately not the case. A recent study found that 70% of all CBD products were mislabeled, either in terms of the concentration of the CBD or in the type of oil (e.g., full-spectrum, broad spectrum, or isolate).

“Consumers looking for high-quality and safe CBD products should be able to trace the hemp oil back to the farm it was grown on and the farming practices use to grow it,” notes Thiel. “Retailers, websites, and trusted sources should have this information readily available.”

At Seed2System, we start with hemp seeds from HGH Seed Inc., a producer that works with Colorado State researchers for quality and consistency. Our vapor distillation process extracts the maximum amount of cannabinoids, terpenes, and flavonoids to produce clean, delicious CBD without harsh solvents or chemicals. We never add flavors, colors, or artificial ingredients, and you can track our CBD products from the seed to your bodily systems.

Still have questions? We’d love to talk to you about how CBD oil for weight loss works! Get in touch or browse our CBD products today.

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